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Physical Chemistry of Epigenetics: Single-Molecule Investigations
[Image: see text] The nucleosome is the fundamental building block of the eukaryotic genome, composed of an ∼147 base-pair DNA fragment wrapping around an octameric histone protein core. DNA and histone proteins are targets of enzymatic chemical modifications that serve as signals for gene regulatio...
| Autor principal: | |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790939/ https://www.ncbi.nlm.nih.gov/pubmed/31404497 http://dx.doi.org/10.1021/acs.jpcb.9b06214 |