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Tamarindus indica Fruit: Pharmacognostical Standardization, Detection of Contaminant, and In Vitro Antioxidant Activity

OBJECTIVE: The main objective of the current study was to perform pharmacognostical, physiochemical analysis and in vitro antioxidant activity of Tamarindus indica Linn. (Family: Fabaceae) fruit. MATERIALS AND METHODS: The present study deals with pharmacognostical characters as identification param...

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Autores principales: Amir, Mohd, Ahmad, Niyaz, Sarfaroz, Md, Ahmad, Wasim, Ahmad, Sayeed, Mujeeb, Mohd, Hyder Pottoo, Faheem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791083/
https://www.ncbi.nlm.nih.gov/pubmed/31619918
http://dx.doi.org/10.4103/jpbs.JPBS_46_19
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author Amir, Mohd
Ahmad, Niyaz
Sarfaroz, Md
Ahmad, Wasim
Ahmad, Sayeed
Mujeeb, Mohd
Hyder Pottoo, Faheem
author_facet Amir, Mohd
Ahmad, Niyaz
Sarfaroz, Md
Ahmad, Wasim
Ahmad, Sayeed
Mujeeb, Mohd
Hyder Pottoo, Faheem
author_sort Amir, Mohd
collection PubMed
description OBJECTIVE: The main objective of the current study was to perform pharmacognostical, physiochemical analysis and in vitro antioxidant activity of Tamarindus indica Linn. (Family: Fabaceae) fruit. MATERIALS AND METHODS: The present study deals with pharmacognostical characters as identification parameters of the fruit, which were subjected to macro- and microscopical studies. Physiochemical analysis was performed as per World Health Organization–recommended parameters. Toxicological parameters such as heavy metals, aflatoxins, and pesticide residue and presence of microbial count were analyzed. This study also deals with the thin layer chromatography/high performance thin layer chromatography fingerprinting and antioxidant activity. RESULTS: The microscopy study revealed the presence of epidermis, vascular bundles, parenchyma cells, mucilage fiber, starch grain, and nonlignified fibers. Physiochemical parameters such as loss on drying, moisture content, ash value, and extractive value were also determined. Heavy metal, aflatoxin, total microbial load, and pesticide residues were found to be variable but under the permissible limits. CONCLUSION: It is critical to analyze these parameters in each crude herbal drug before further processing to ensure their safety and efficacy for better approval at the international podium. This study revealed precise identification for the meticulous crude drug which will be valuable in detection and manage to adulterations of the raw material.
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spelling pubmed-67910832019-10-16 Tamarindus indica Fruit: Pharmacognostical Standardization, Detection of Contaminant, and In Vitro Antioxidant Activity Amir, Mohd Ahmad, Niyaz Sarfaroz, Md Ahmad, Wasim Ahmad, Sayeed Mujeeb, Mohd Hyder Pottoo, Faheem J Pharm Bioallied Sci Original Article OBJECTIVE: The main objective of the current study was to perform pharmacognostical, physiochemical analysis and in vitro antioxidant activity of Tamarindus indica Linn. (Family: Fabaceae) fruit. MATERIALS AND METHODS: The present study deals with pharmacognostical characters as identification parameters of the fruit, which were subjected to macro- and microscopical studies. Physiochemical analysis was performed as per World Health Organization–recommended parameters. Toxicological parameters such as heavy metals, aflatoxins, and pesticide residue and presence of microbial count were analyzed. This study also deals with the thin layer chromatography/high performance thin layer chromatography fingerprinting and antioxidant activity. RESULTS: The microscopy study revealed the presence of epidermis, vascular bundles, parenchyma cells, mucilage fiber, starch grain, and nonlignified fibers. Physiochemical parameters such as loss on drying, moisture content, ash value, and extractive value were also determined. Heavy metal, aflatoxin, total microbial load, and pesticide residues were found to be variable but under the permissible limits. CONCLUSION: It is critical to analyze these parameters in each crude herbal drug before further processing to ensure their safety and efficacy for better approval at the international podium. This study revealed precise identification for the meticulous crude drug which will be valuable in detection and manage to adulterations of the raw material. Wolters Kluwer - Medknow 2019 /pmc/articles/PMC6791083/ /pubmed/31619918 http://dx.doi.org/10.4103/jpbs.JPBS_46_19 Text en Copyright: © 2019 Journal of Pharmacy and Bioallied Sciences http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Amir, Mohd
Ahmad, Niyaz
Sarfaroz, Md
Ahmad, Wasim
Ahmad, Sayeed
Mujeeb, Mohd
Hyder Pottoo, Faheem
Tamarindus indica Fruit: Pharmacognostical Standardization, Detection of Contaminant, and In Vitro Antioxidant Activity
title Tamarindus indica Fruit: Pharmacognostical Standardization, Detection of Contaminant, and In Vitro Antioxidant Activity
title_full Tamarindus indica Fruit: Pharmacognostical Standardization, Detection of Contaminant, and In Vitro Antioxidant Activity
title_fullStr Tamarindus indica Fruit: Pharmacognostical Standardization, Detection of Contaminant, and In Vitro Antioxidant Activity
title_full_unstemmed Tamarindus indica Fruit: Pharmacognostical Standardization, Detection of Contaminant, and In Vitro Antioxidant Activity
title_short Tamarindus indica Fruit: Pharmacognostical Standardization, Detection of Contaminant, and In Vitro Antioxidant Activity
title_sort tamarindus indica fruit: pharmacognostical standardization, detection of contaminant, and in vitro antioxidant activity
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791083/
https://www.ncbi.nlm.nih.gov/pubmed/31619918
http://dx.doi.org/10.4103/jpbs.JPBS_46_19
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