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Tamarindus indica Fruit: Pharmacognostical Standardization, Detection of Contaminant, and In Vitro Antioxidant Activity
OBJECTIVE: The main objective of the current study was to perform pharmacognostical, physiochemical analysis and in vitro antioxidant activity of Tamarindus indica Linn. (Family: Fabaceae) fruit. MATERIALS AND METHODS: The present study deals with pharmacognostical characters as identification param...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791083/ https://www.ncbi.nlm.nih.gov/pubmed/31619918 http://dx.doi.org/10.4103/jpbs.JPBS_46_19 |
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author | Amir, Mohd Ahmad, Niyaz Sarfaroz, Md Ahmad, Wasim Ahmad, Sayeed Mujeeb, Mohd Hyder Pottoo, Faheem |
author_facet | Amir, Mohd Ahmad, Niyaz Sarfaroz, Md Ahmad, Wasim Ahmad, Sayeed Mujeeb, Mohd Hyder Pottoo, Faheem |
author_sort | Amir, Mohd |
collection | PubMed |
description | OBJECTIVE: The main objective of the current study was to perform pharmacognostical, physiochemical analysis and in vitro antioxidant activity of Tamarindus indica Linn. (Family: Fabaceae) fruit. MATERIALS AND METHODS: The present study deals with pharmacognostical characters as identification parameters of the fruit, which were subjected to macro- and microscopical studies. Physiochemical analysis was performed as per World Health Organization–recommended parameters. Toxicological parameters such as heavy metals, aflatoxins, and pesticide residue and presence of microbial count were analyzed. This study also deals with the thin layer chromatography/high performance thin layer chromatography fingerprinting and antioxidant activity. RESULTS: The microscopy study revealed the presence of epidermis, vascular bundles, parenchyma cells, mucilage fiber, starch grain, and nonlignified fibers. Physiochemical parameters such as loss on drying, moisture content, ash value, and extractive value were also determined. Heavy metal, aflatoxin, total microbial load, and pesticide residues were found to be variable but under the permissible limits. CONCLUSION: It is critical to analyze these parameters in each crude herbal drug before further processing to ensure their safety and efficacy for better approval at the international podium. This study revealed precise identification for the meticulous crude drug which will be valuable in detection and manage to adulterations of the raw material. |
format | Online Article Text |
id | pubmed-6791083 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-67910832019-10-16 Tamarindus indica Fruit: Pharmacognostical Standardization, Detection of Contaminant, and In Vitro Antioxidant Activity Amir, Mohd Ahmad, Niyaz Sarfaroz, Md Ahmad, Wasim Ahmad, Sayeed Mujeeb, Mohd Hyder Pottoo, Faheem J Pharm Bioallied Sci Original Article OBJECTIVE: The main objective of the current study was to perform pharmacognostical, physiochemical analysis and in vitro antioxidant activity of Tamarindus indica Linn. (Family: Fabaceae) fruit. MATERIALS AND METHODS: The present study deals with pharmacognostical characters as identification parameters of the fruit, which were subjected to macro- and microscopical studies. Physiochemical analysis was performed as per World Health Organization–recommended parameters. Toxicological parameters such as heavy metals, aflatoxins, and pesticide residue and presence of microbial count were analyzed. This study also deals with the thin layer chromatography/high performance thin layer chromatography fingerprinting and antioxidant activity. RESULTS: The microscopy study revealed the presence of epidermis, vascular bundles, parenchyma cells, mucilage fiber, starch grain, and nonlignified fibers. Physiochemical parameters such as loss on drying, moisture content, ash value, and extractive value were also determined. Heavy metal, aflatoxin, total microbial load, and pesticide residues were found to be variable but under the permissible limits. CONCLUSION: It is critical to analyze these parameters in each crude herbal drug before further processing to ensure their safety and efficacy for better approval at the international podium. This study revealed precise identification for the meticulous crude drug which will be valuable in detection and manage to adulterations of the raw material. Wolters Kluwer - Medknow 2019 /pmc/articles/PMC6791083/ /pubmed/31619918 http://dx.doi.org/10.4103/jpbs.JPBS_46_19 Text en Copyright: © 2019 Journal of Pharmacy and Bioallied Sciences http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Amir, Mohd Ahmad, Niyaz Sarfaroz, Md Ahmad, Wasim Ahmad, Sayeed Mujeeb, Mohd Hyder Pottoo, Faheem Tamarindus indica Fruit: Pharmacognostical Standardization, Detection of Contaminant, and In Vitro Antioxidant Activity |
title | Tamarindus indica Fruit: Pharmacognostical Standardization, Detection of Contaminant, and In Vitro Antioxidant Activity |
title_full | Tamarindus indica Fruit: Pharmacognostical Standardization, Detection of Contaminant, and In Vitro Antioxidant Activity |
title_fullStr | Tamarindus indica Fruit: Pharmacognostical Standardization, Detection of Contaminant, and In Vitro Antioxidant Activity |
title_full_unstemmed | Tamarindus indica Fruit: Pharmacognostical Standardization, Detection of Contaminant, and In Vitro Antioxidant Activity |
title_short | Tamarindus indica Fruit: Pharmacognostical Standardization, Detection of Contaminant, and In Vitro Antioxidant Activity |
title_sort | tamarindus indica fruit: pharmacognostical standardization, detection of contaminant, and in vitro antioxidant activity |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791083/ https://www.ncbi.nlm.nih.gov/pubmed/31619918 http://dx.doi.org/10.4103/jpbs.JPBS_46_19 |
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