Cargando…

Synthesis of some novel dibromo-2-arylquinazolinone derivatives as cytotoxic agents

Recently the quinazoline derivatives have attracted much attention for their anticancer properties. In this study a series of new brominated quinazoline derivatives (1a-1g) were synthesized in two steps. In the first step we used N-bromosuccinimide to brominate the anthranilamid. Then in the second...

Descripción completa

Detalles Bibliográficos
Autores principales:	Faghih, Zeinab, Rahmannejadi, Nasrin, Sabet, Razieh, Zomorodian, Kamiar, Asad, Mohammad, Khabnadideh, Soghra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer - Medknow 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791173/ https://www.ncbi.nlm.nih.gov/pubmed/31620187 http://dx.doi.org/10.4103/1735-5362.253358

Ejemplares similares

Quinazoline analogues as cytotoxic agents; QSAR, docking, and in silico studies
por: Emami, Leila, et al.
Publicado: (2021)

Nano-SnCl(4).SiO(2), an efficient catalyst for synthesis of benzimidazole drivatives as antifungal and cytotoxic agents
por: Zamani, Leila, et al.
Publicado: (2019)

Design, synthesis, computational study and cytotoxic evaluation of some new quinazoline derivatives containing pyrimidine moiety
por: Zare, Somayeh, et al.
Publicado: (2023)

Design, Synthesis, and Biological Activity of New Triazole and Nitro-Triazole Derivatives as Antifungal Agents
por: Sadeghpour, Hossein, et al.
Publicado: (2017)

Synthesis, biological evaluation, and computational studies of some novel quinazoline derivatives as anticancer agents
por: Emami, Leila, et al.
Publicado: (2022)

Design, Synthesis, and Antifungal Activity of New α-Aminophosphonates
por: Rezaei, Zahra, et al.
Publicado: (2011)

Barium silicate nanoparticles, an efficient catalyst for one-pot green synthesis of α-benzyl amino coumarin derivatives as potential chemotherapeutic agents
por: Taghrir, Hadi, et al.
Publicado: (2023)

Docking, Synthesis and Evaluation of the Antifungal Activity of Pyrimido [4,5-b]quinolins
por: Araghi, Reza, et al.
Publicado: (2020)

Design, synthesis and evaluation of novel 1,2,4-triazole derivatives as promising anticancer agents
por: Emami, Leila, et al.
Publicado: (2022)

Design, Synthesis, Biological Evaluation and Molecular Modeling Study of Novel Indolizine-1-Carbonitrile Derivatives as Potential Anti-Microbial Agents
por: Faghih-Mirzaei, Ehsan, et al.
Publicado: (2018)

Rhodium-Catalyzed Merging of 2-Arylquinazolinone and 2,2-Difluorovinyl Tosylate: Diverse Synthesis of Monofluoroolefin Quinazolinone Derivatives
por: Wang, Ning, et al.
Publicado: (2020)

Brønsted acid-catalysed enantioselective construction of axially chiral arylquinazolinones
por: Wang, Yong-Bin, et al.
Publicado: (2017)

Binding mode of triazole derivatives as aromatase inhibitors based on docking, protein ligand interaction fingerprinting, and molecular dynamics simulation studies
por: Mojaddami, Ayyub, et al.
Publicado: (2017)

Synthesis and antifungal activity of benzimidazole, benzotriazole and aminothiazole derivatives
por: Khabnadideh, S., et al.
Publicado: (2012)

A novel heterogeneous acid–base nano-catalyst designed based on graphene oxide for synthesis of spiro-indoline-pyranochromene derivatives
por: Khabnadideh, Soghra, et al.
Publicado: (2023)

Structure based design and anti-breast cancer evaluation of some novel 4-anilinoquinazoline derivatives as potential epidermal growth factor receptor inhibitors
por: Haghighijoo, Zahra, et al.
Publicado: (2018)

Biotransformation of acetoin to 2,3-butanediol: Assessment of plant and microbial biocatalysts
por: Javidnia, Katayoun, et al.
Publicado: (2016)

The Cutaneous Bacterial Microflora of the Bodybuilders Using Anabolic-Androgenic Steroids
por: Zomorodian, Kamiar, et al.
Publicado: (2014)

Design and synthesis of novel nitrothiazolacetamide conjugated to different thioquinazolinone derivatives as anti-urease agents
por: Sohrabi, Marzieh, et al.
Publicado: (2022)

Synthesis, Molecular Docking and Cytotoxic Activity Evaluation of Organometallic Thiolated Gold(I) Complexes
por: Faghih, Zeinab, et al.
Publicado: (2020)

Synthesis, molecular docking, and cytotoxicity of quinazolinone and dihydroquinazolinone derivatives as cytotoxic agents
por: Taayoshi, Fahimeh, et al.
Publicado: (2022)

A Comparative QSAR Analysis, Molecular Docking and PLIF Studies of Some N-arylphenyl-2, 2-Dichloroacetamide Analogues as Anticancer Agents
por: Fereidoonnezhad, Masood, et al.
Publicado: (2017)

Synthesis and cytotoxic evaluation of some derivatives of triazole-quinazolinone hybrids
por: Hassanzadeh, Farshid, et al.
Publicado: (2019)

Synthesis of Some Oxadiazole Derivatives as New Anticandidal Agents
por: Kaplancikli, Zafer Asim
Publicado: (2011)

Synthesis and Analgesic Activity of Some New Pyrazoles and Triazoles Bearing a 6,8-Dibromo-2-methylquinazoline Moiety
por: Saad, Hosam A., et al.
Publicado: (2011)

Efficient synthesis of 1,3-naphtoxazine derivatives using reusable magnetic catalyst (GO-Fe(3)O(4)–Ti((IV))): anticonvulsant evaluation and computational studies
por: Khabnadideh, Soghra, et al.
Publicado: (2022)

Synthesis and Cytotoxic Evaluation of Some Substituted 5-Pyrazolones and Their Urea Derivatives
por: Gediz Erturk, Aliye, et al.
Publicado: (2020)

Synthesis of N-arylmethyl Substituted Indole Derivatives as New Antiplatelet Aggregation Agents
por: Faghih Akhlaghi, Masoud, et al.
Publicado: (2014)

Direct molecular analysis of Malassezia species from the clinical samples of patients with pityriasis versicolor
por: Eghtedarnejad, Esmaeil, et al.
Publicado: (2023)

Synthesis of Some New Tetrahydropyrimidine Derivatives as Possible Antibacterial Agents
por: Foroughifar, Naser, et al.
Publicado: (2017)

Synthesis, Cytotoxic Activity and 2D-QSAR Study of Some Imidazoquinazoline Derivatives
por: Georgey, Hanan
Publicado: (2014)

Synthesis and Evaluation of Some 17-Acetamidoandrostane and N,N-Dimethyl-7-deoxycholic Amide Derivatives as Cytotoxic Agents: Structure/Activity Studies
por: Huang, Yanmin, et al.
Publicado: (2013)

Synthesis of hydroxycinnamic acid derivatives as mitochondria-targeted antioxidants and cytotoxic agents
por: Li, Jiyu, et al.
Publicado: (2017)

Synthesis and cytotoxic evaluation of novel quinazolinone derivatives as potential anticancer agents
por: Poorirani, Safoora, et al.
Publicado: (2018)

Design, Synthesis and Biological Evaluation of Novel Piperazinone Derivatives as Cytotoxic Agents
por: Ghasemi, Saeed, et al.
Publicado: (2020)

Synthesis and bioactivity evaluation of pachymic acid derivatives as potential cytotoxic agents
por: Wang, Hezhen, et al.
Publicado: (2022)

Synthesis of Some Novel Heterocyclic and Schiff Base Derivatives as Antimicrobial Agents
por: Azab, Mohamed E., et al.
Publicado: (2015)

Three-Component Synthesis of Some New Coumarin Derivatives as Anticancer Agents
por: Alshabanah, Latifah A., et al.
Publicado: (2022)

2,5-Dibromopyridine
por: Al-Far, Rawhi H., et al.
Publicado: (2009)

6,8-Dibromoquinoline
por: Çelik, Ísmail, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_mnpo695h07mnfth5461qola52n