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Spica Prunellae Extract Enhances Fluorouracil Sensitivity of 5-Fluorouracil-Resistant Human Colon Carcinoma HCT-8/5-FU Cells via TOP2α and miR-494

The use of 5-fluorouracil (5-FU) has been proven benefits, but it also has adverse events in colorectal cancer (CRC) chemotherapy. In this study, we explored the mechanism of 5-FU resistance by bioinformatics analysis of the NCBI public dataset series GSE81005. Fifteen hub genes were screened out of...

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Detalles Bibliográficos
Autores principales:	Fang, Yi, Yang, Chi, Zhang, Ling, Wei, Lihui, Lin, Jiumao, Zhao, Jinyan, Peng, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791265/ https://www.ncbi.nlm.nih.gov/pubmed/31662984 http://dx.doi.org/10.1155/2019/5953619

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