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A poly-neoantigen DNA vaccine synergizes with PD-1 blockade to induce T cell-mediated tumor control
The combination of immune-stimulating strategies has the potency to improve immunotherapy of cancer. Vaccination against neoepitopes derived from patient tumor material can generate tumor-specific T cell immunity, which could reinforce the efficacy of checkpoint inhibitor therapies such as anti-PD-1...
Autores principales: | Tondini, Elena, Arakelian, Tsolere, Oosterhuis, Koen, Camps, Marcel, van Duikeren, Suzanne, Han, Wanda, Arens, Ramon, Zondag, Gerben, van Bergen, Jeroen, Ossendorp, Ferry |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791440/ https://www.ncbi.nlm.nih.gov/pubmed/31646082 http://dx.doi.org/10.1080/2162402X.2019.1652539 |
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