Suppression of tumor antigen presentation during aneuploid tumor evolution contributes to immune evasion

Anti-tumor immune responses impede tumor formation, and cancers have evolved many mechanisms of immune evasion. Confirming earlier findings, we show that human tumors with high chromosomal instability (CIN+) are significantly less immunogenic, as judged by tumor lymphocyte infiltration, compared to...

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Detalles Bibliográficos
Autores principales: Tripathi, Reshmi, Modur, Vishnu, Senovilla, Laura, Kroemer, Guido, Komurov, Kakajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791449/
https://www.ncbi.nlm.nih.gov/pubmed/31646083
http://dx.doi.org/10.1080/2162402X.2019.1657374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791449/
https://www.ncbi.nlm.nih.gov/pubmed/31646083
http://dx.doi.org/10.1080/2162402X.2019.1657374

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