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Suppression of tumor antigen presentation during aneuploid tumor evolution contributes to immune evasion
Anti-tumor immune responses impede tumor formation, and cancers have evolved many mechanisms of immune evasion. Confirming earlier findings, we show that human tumors with high chromosomal instability (CIN+) are significantly less immunogenic, as judged by tumor lymphocyte infiltration, compared to...
Autores principales: | Tripathi, Reshmi, Modur, Vishnu, Senovilla, Laura, Kroemer, Guido, Komurov, Kakajan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791449/ https://www.ncbi.nlm.nih.gov/pubmed/31646083 http://dx.doi.org/10.1080/2162402X.2019.1657374 |
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