A synergistic triad of chemotherapy, immune checkpoint inhibitors, and caloric restriction mimetics eradicates tumors in mice

We have recently shown that chemotherapy with immunogenic cell death (ICD)-inducing agents can be advantageously combined with fasting regimens or caloric restriction mimetics (CRMs) to achieve superior tumor growth control via a T cell-dependent mechanism. Here, we show that the blockade of the CD1...

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Detalles Bibliográficos
Autores principales: Lévesque, Sarah, Le Naour, Julie, Pietrocola, Federico, Paillet, Juliette, Kremer, Margerie, Castoldi, Francesca, Baracco, Elisa E., Wang, Yan, Vacchelli, Erika, Stoll, Gautier, Jolly, Ariane, De La Grange, Pierre, Zitvogel, Laurence, Kroemer, Guido, Pol, Jonathan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791453/
https://www.ncbi.nlm.nih.gov/pubmed/31646107
http://dx.doi.org/10.1080/2162402X.2019.1657375

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