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Dexamethasone differentially depletes tumour and peripheral blood lymphocytes and can impact the efficacy of chemotherapy/checkpoint blockade combination treatment
Dexamethasone is a synthetic glucocorticoid commonly used for the prevention and management of side effects in cancer patients undergoing chemotherapy. While it is effective as an anti-emetic and in preventing hypersensitivity reactions, dexamethasone depletes peripheral blood lymphocytes and impact...
Autores principales: | Aston, Wayne J., Hope, Danika E., Cook, Alistair M., Boon, Louis, Dick, Ian, Nowak, Anna K., Lake, Richard A., Lesterhuis, W. Joost |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791454/ https://www.ncbi.nlm.nih.gov/pubmed/31646089 http://dx.doi.org/10.1080/2162402X.2019.1641390 |
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