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ANO4 (Anoctamin 4) Is a Novel Marker of Zona Glomerulosa That Regulates Stimulated Aldosterone Secretion
Microarray comparison of the transcriptomes of human adrenal zona glomerulosa (ZG) and zona fasciculata found several ZG-specific genes that negatively regulate aldosterone secretion. The third and most significantly upregulated ZG-gene (19.9-fold compared with zona fasciculata, P=6.58×10(−24)) was...
Autores principales: | Maniero, Carmela, Scudieri, Paolo, Haris Shaikh, Lalarukh, Zhao, Wanfeng, Gurnell, Mark, Galietta, Luis J.V., Brown, Morris J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott, Williams & Wilkins
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791498/ https://www.ncbi.nlm.nih.gov/pubmed/31564164 http://dx.doi.org/10.1161/HYPERTENSIONAHA.119.13287 |
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