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Mechanisms of failure of chimeric antigen receptor T-cell therapy

Although chimeric antigen receptor T (CART)-cell therapy is best recognized for its antitumor effect in relapsed/refractory B-cell hematological cancers, it is still associated with a high relapse rate. RECENT FINDINGS: We firstly analyzed internal immunological and genetic reasons of CD19+ relapse...

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Detalles Bibliográficos
Autores principales:	Li, Xiaoqing, Chen, Weihong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams And Wilkins 2019
Materias:	HEMATOPOIETIC STEM CELL TRANSPLANTATION: Edited by David Rizzieri
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791516/ https://www.ncbi.nlm.nih.gov/pubmed/31577606 http://dx.doi.org/10.1097/MOH.0000000000000548

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