Celiac Disease in a 16-Month-Old Child Presenting as Motor Regression

Neurodevelopmental symptoms were previously believed to be a complication of celiac disease (CD) and rarely seen as presenting symptoms. One case has been reported so far where motor regression was the presenting symptom. We present a 16-month-old girl with postprandial vomiting and regression of mo...

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Autores principales: Bashir, Anam, Mousattat, Youmna, Lawson, April, Patel, Pratikkumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791607/
https://www.ncbi.nlm.nih.gov/pubmed/31737722
http://dx.doi.org/10.14309/crj.0000000000000192
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author Bashir, Anam
Mousattat, Youmna
Lawson, April
Patel, Pratikkumar
author_facet Bashir, Anam
Mousattat, Youmna
Lawson, April
Patel, Pratikkumar
author_sort Bashir, Anam
collection PubMed
description Neurodevelopmental symptoms were previously believed to be a complication of celiac disease (CD) and rarely seen as presenting symptoms. One case has been reported so far where motor regression was the presenting symptom. We present a 16-month-old girl with postprandial vomiting and regression of motor skills. Examination revealed abdominal distension, hypotonia, and decreased motor movements in lower extremities. Celiac serology showed elevated tissue transglutaminase (tTG) immunoglobulin A (IgA) levels. Esophagogastroduodenoscopy with biopsies confirmed CD. Gluten-free diet led to the improvement of neurological and gastrointestinal complaints. We recommend keeping CD as one of the differentials in children with neurodevelopmental symptoms.
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spelling pubmed-67916072019-11-15 Celiac Disease in a 16-Month-Old Child Presenting as Motor Regression Bashir, Anam Mousattat, Youmna Lawson, April Patel, Pratikkumar ACG Case Rep J Case Report Neurodevelopmental symptoms were previously believed to be a complication of celiac disease (CD) and rarely seen as presenting symptoms. One case has been reported so far where motor regression was the presenting symptom. We present a 16-month-old girl with postprandial vomiting and regression of motor skills. Examination revealed abdominal distension, hypotonia, and decreased motor movements in lower extremities. Celiac serology showed elevated tissue transglutaminase (tTG) immunoglobulin A (IgA) levels. Esophagogastroduodenoscopy with biopsies confirmed CD. Gluten-free diet led to the improvement of neurological and gastrointestinal complaints. We recommend keeping CD as one of the differentials in children with neurodevelopmental symptoms. Wolters Kluwer 2019-08-27 /pmc/articles/PMC6791607/ /pubmed/31737722 http://dx.doi.org/10.14309/crj.0000000000000192 Text en © 2019 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Case Report
Bashir, Anam
Mousattat, Youmna
Lawson, April
Patel, Pratikkumar
Celiac Disease in a 16-Month-Old Child Presenting as Motor Regression
title Celiac Disease in a 16-Month-Old Child Presenting as Motor Regression
title_full Celiac Disease in a 16-Month-Old Child Presenting as Motor Regression
title_fullStr Celiac Disease in a 16-Month-Old Child Presenting as Motor Regression
title_full_unstemmed Celiac Disease in a 16-Month-Old Child Presenting as Motor Regression
title_short Celiac Disease in a 16-Month-Old Child Presenting as Motor Regression
title_sort celiac disease in a 16-month-old child presenting as motor regression
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791607/
https://www.ncbi.nlm.nih.gov/pubmed/31737722
http://dx.doi.org/10.14309/crj.0000000000000192
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