Acute Colonic Pseudo-Obstruction as a Manifestation of Lead Intoxication in a Conservator

We report a case of a 39-year-old art conservator who presented complaining of abdominal pain and constipation. His laboratory results showed normocytic normochromic anemia and abnormal liver tests. Computed tomography revealed distention of the whole colon without obstruction. Evaluation of anemia...

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Detalles Bibliográficos
Autores principales: Costa-Moreira, Pedro, Coelho, Rosa, Pita, Inês, Macedo, Guilherme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791627/
https://www.ncbi.nlm.nih.gov/pubmed/31737709
http://dx.doi.org/10.14309/crj.0000000000000171
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author Costa-Moreira, Pedro
Coelho, Rosa
Pita, Inês
Macedo, Guilherme
author_facet Costa-Moreira, Pedro
Coelho, Rosa
Pita, Inês
Macedo, Guilherme
author_sort Costa-Moreira, Pedro
collection PubMed
description We report a case of a 39-year-old art conservator who presented complaining of abdominal pain and constipation. His laboratory results showed normocytic normochromic anemia and abnormal liver tests. Computed tomography revealed distention of the whole colon without obstruction. Evaluation of anemia was compatible with nonimmune hemolysis. A liver biopsy showed accumulation of ferric pigment in Kupffer cells. Given the typical findings in the blood smear and the epidemiological context, a serum lead assay was performed (92 μg/dL). This clinical case illustrates the need for gastroenterologists to recognize digestive manifestations of systemic diseases, including intoxications.
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spelling pubmed-67916272019-11-15 Acute Colonic Pseudo-Obstruction as a Manifestation of Lead Intoxication in a Conservator Costa-Moreira, Pedro Coelho, Rosa Pita, Inês Macedo, Guilherme ACG Case Rep J Case Report We report a case of a 39-year-old art conservator who presented complaining of abdominal pain and constipation. His laboratory results showed normocytic normochromic anemia and abnormal liver tests. Computed tomography revealed distention of the whole colon without obstruction. Evaluation of anemia was compatible with nonimmune hemolysis. A liver biopsy showed accumulation of ferric pigment in Kupffer cells. Given the typical findings in the blood smear and the epidemiological context, a serum lead assay was performed (92 μg/dL). This clinical case illustrates the need for gastroenterologists to recognize digestive manifestations of systemic diseases, including intoxications. Wolters Kluwer 2019-08-30 /pmc/articles/PMC6791627/ /pubmed/31737709 http://dx.doi.org/10.14309/crj.0000000000000171 Text en © 2019 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Case Report
Costa-Moreira, Pedro
Coelho, Rosa
Pita, Inês
Macedo, Guilherme
Acute Colonic Pseudo-Obstruction as a Manifestation of Lead Intoxication in a Conservator
title Acute Colonic Pseudo-Obstruction as a Manifestation of Lead Intoxication in a Conservator
title_full Acute Colonic Pseudo-Obstruction as a Manifestation of Lead Intoxication in a Conservator
title_fullStr Acute Colonic Pseudo-Obstruction as a Manifestation of Lead Intoxication in a Conservator
title_full_unstemmed Acute Colonic Pseudo-Obstruction as a Manifestation of Lead Intoxication in a Conservator
title_short Acute Colonic Pseudo-Obstruction as a Manifestation of Lead Intoxication in a Conservator
title_sort acute colonic pseudo-obstruction as a manifestation of lead intoxication in a conservator
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791627/
https://www.ncbi.nlm.nih.gov/pubmed/31737709
http://dx.doi.org/10.14309/crj.0000000000000171
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