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Hypokalemia-Induced Rhabdomyolysis From Budesonide Therapy in Crohn's Disease

We present a 71-year-old white man with active ileocolonic Crohn's disease, recently started on budesonide therapy, who presented with extreme weakness and muscle aches. He was diagnosed with hypokalemia-induced rhabdomyolysis, 3 weeks after starting budesonide therapy. His symptoms and laborat...

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Detalles Bibliográficos
Autores principales: Mansour, Ramy, Mandiga, Pujyitha, Thigpin, Derek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791640/
https://www.ncbi.nlm.nih.gov/pubmed/31737729
http://dx.doi.org/10.14309/crj.0000000000000201
Descripción
Sumario:We present a 71-year-old white man with active ileocolonic Crohn's disease, recently started on budesonide therapy, who presented with extreme weakness and muscle aches. He was diagnosed with hypokalemia-induced rhabdomyolysis, 3 weeks after starting budesonide therapy. His symptoms and laboratory values improved with budesonide discontinuation and appropriate fluid and electrolyte replacement. This is only the second case of hypokalemia-induced rhabdomyolysis secondary to budesonide.