Colonic Wall Thickening as the First Indicator of Relapse of Acute Lymphoblastic Leukemia

The gastrointestinal (GI) tract is a rarely reported site of extramedullary relapse of acute lymphoblastic leukemia (ALL). We report a patient being effectively treated with immunotherapy for relapsed ALL who was incidentally noted to have colonic wall thickening on imaging that was subsequently pat...

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Autores principales: Hathorn, Kelly E., Luskin, Marlise R., Caton, Michael Travis, DeAngelo, Daniel J., Saltzman, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791643/
https://www.ncbi.nlm.nih.gov/pubmed/31737733
http://dx.doi.org/10.14309/crj.0000000000000207
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author Hathorn, Kelly E.
Luskin, Marlise R.
Caton, Michael Travis
DeAngelo, Daniel J.
Saltzman, John R.
author_facet Hathorn, Kelly E.
Luskin, Marlise R.
Caton, Michael Travis
DeAngelo, Daniel J.
Saltzman, John R.
author_sort Hathorn, Kelly E.
collection PubMed
description The gastrointestinal (GI) tract is a rarely reported site of extramedullary relapse of acute lymphoblastic leukemia (ALL). We report a patient being effectively treated with immunotherapy for relapsed ALL who was incidentally noted to have colonic wall thickening on imaging that was subsequently pathologically confirmed to be the result of disease infiltration of colonic tissue. Primary ALL involvement of the GI tract should be considered in the evaluation of GI complaints in patients with ALL, particularly those with relapsed disease otherwise effectively treated with immunotherapy.
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spelling pubmed-67916432019-11-15 Colonic Wall Thickening as the First Indicator of Relapse of Acute Lymphoblastic Leukemia Hathorn, Kelly E. Luskin, Marlise R. Caton, Michael Travis DeAngelo, Daniel J. Saltzman, John R. ACG Case Rep J Case Report The gastrointestinal (GI) tract is a rarely reported site of extramedullary relapse of acute lymphoblastic leukemia (ALL). We report a patient being effectively treated with immunotherapy for relapsed ALL who was incidentally noted to have colonic wall thickening on imaging that was subsequently pathologically confirmed to be the result of disease infiltration of colonic tissue. Primary ALL involvement of the GI tract should be considered in the evaluation of GI complaints in patients with ALL, particularly those with relapsed disease otherwise effectively treated with immunotherapy. Wolters Kluwer 2019-09-02 /pmc/articles/PMC6791643/ /pubmed/31737733 http://dx.doi.org/10.14309/crj.0000000000000207 Text en © 2019 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Case Report
Hathorn, Kelly E.
Luskin, Marlise R.
Caton, Michael Travis
DeAngelo, Daniel J.
Saltzman, John R.
Colonic Wall Thickening as the First Indicator of Relapse of Acute Lymphoblastic Leukemia
title Colonic Wall Thickening as the First Indicator of Relapse of Acute Lymphoblastic Leukemia
title_full Colonic Wall Thickening as the First Indicator of Relapse of Acute Lymphoblastic Leukemia
title_fullStr Colonic Wall Thickening as the First Indicator of Relapse of Acute Lymphoblastic Leukemia
title_full_unstemmed Colonic Wall Thickening as the First Indicator of Relapse of Acute Lymphoblastic Leukemia
title_short Colonic Wall Thickening as the First Indicator of Relapse of Acute Lymphoblastic Leukemia
title_sort colonic wall thickening as the first indicator of relapse of acute lymphoblastic leukemia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791643/
https://www.ncbi.nlm.nih.gov/pubmed/31737733
http://dx.doi.org/10.14309/crj.0000000000000207
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