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TIN2 Functions with TPP1/POT1 To Stimulate Telomerase Processivity
TIN2 is an important regulator of telomere length, and mutations in TINF2, the gene encoding TIN2, cause short-telomere syndromes. While the genetics underscore the importance of TIN2, the mechanism through which TIN2 regulates telomere length remains unclear. Here, we tested the effects of human TI...
Autores principales: | Pike, Alexandra M., Strong, Margaret A., Ouyang, John Paul T., Greider, Carol W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791651/ https://www.ncbi.nlm.nih.gov/pubmed/31383750 http://dx.doi.org/10.1128/MCB.00593-18 |
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