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Coopted temporal patterning governs cellular hierarchy, heterogeneity and metabolism in Drosophila neuroblast tumors

It is still unclear what drives progression of childhood tumors. During Drosophila larval development, asymmetrically-dividing neural stem cells, called neuroblasts, progress through an intrinsic temporal patterning program that ensures cessation of divisions before adulthood. We previously showed t...

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Detalles Bibliográficos
Autores principales:	Genovese, Sara, Clément, Raphaël, Gaultier, Cassandra, Besse, Florence, Narbonne-Reveau, Karine, Daian, Fabrice, Foppolo, Sophie, Luis, Nuno Miguel, Maurange, Cédric
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2019
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791719/ https://www.ncbi.nlm.nih.gov/pubmed/31566561 http://dx.doi.org/10.7554/eLife.50375

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