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Redirecting the immune response towards immunoprotective domains of a DNABII protein resolves experimental otitis media
The chronicity and recurrence of many bacterial diseases is largely attributable to the presence of a biofilm, and eradication of these structures is confounded by an extracellular DNA-rich matrix. DNABII proteins, including integration host factor (IHF), are critical components of the matrix formed...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791836/ https://www.ncbi.nlm.nih.gov/pubmed/31632744 http://dx.doi.org/10.1038/s41541-019-0137-1 |