IRF2 is a master regulator of human keratinocyte stem cell fate

Resident adult epithelial stem cells maintain tissue homeostasis by balancing self-renewal and differentiation. The stem cell potential of human epidermal keratinocytes is retained in vitro but lost over time suggesting extrinsic and intrinsic regulation. Transcription factor-controlled regulatory c...

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Detalles Bibliográficos
Autores principales: Mercado, Nicolas, Schutzius, Gabi, Kolter, Christian, Estoppey, David, Bergling, Sebastian, Roma, Guglielmo, Gubser Keller, Caroline, Nigsch, Florian, Salathe, Adrian, Terranova, Remi, Reece-Hoyes, John, Alford, John, Russ, Carsten, Knehr, Judith, Hoepfner, Dominic, Aebi, Alexandra, Ruffner, Heinz, Beck, Tanner C., Jagannathan, Sajjeev, Olson, Calla M., Sheppard, Hadley E., Elsarrag, Selma Z., Bouwmeester, Tewis, Frederiksen, Mathias, Lohmann, Felix, Lin, Charles Y., Kirkland, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791852/
https://www.ncbi.nlm.nih.gov/pubmed/31611556
http://dx.doi.org/10.1038/s41467-019-12559-x

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