Endothelial cell pyroptosis plays an important role in Kawasaki disease via HMGB1/RAGE/cathespin B signaling pathway and NLRP3 inflammasome activation

Kawasaki disease (KD) is the most common cause of pediatric cardiac disease in developed countries, and can lead to permanent coronary artery damage and long term sequelae such as coronary artery aneurysms. Given the prevalence and severity of KD, further research is warranted on its pathophysiology...

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Detalles Bibliográficos
Autores principales: Jia, Chang, Zhang, Jian, Chen, Huanwen, Zhuge, Yingzhi, Chen, Huiqiao, Qian, Fanyu, Zhou, Kailiang, Niu, Chao, Wang, Fangyan, Qiu, Huixian, Wang, Zhenquan, Xiao, Jian, Rong, Xing, Chu, Maoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791856/
https://www.ncbi.nlm.nih.gov/pubmed/31611559
http://dx.doi.org/10.1038/s41419-019-2021-3

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