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Dual Inhibition of Pirarubicin-Induced AKT and ERK Activations by Phenformin Sensitively Suppresses Bladder Cancer Growth

Activations of Akt or ERK pathway induced by clinical drugs promote therapeutic failure due to decrease of drug response, and no available strategies have been developed to solve these problems. In this study, we found that pirarubicin (THP), one important chemotherapeutic drug for treating bladder...

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Detalles Bibliográficos
Autores principales:	Peng, Mei, Deng, Jun, Zhou, Sichun, Xiao, Di, Long, Jiahui, Zhang, Nan, He, Caimei, Mo, Miao, Yang, Xiaoping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791928/ https://www.ncbi.nlm.nih.gov/pubmed/31649535 http://dx.doi.org/10.3389/fphar.2019.01159

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