Cargando…

Cyclin F‐dependent degradation of E2F7 is critical for DNA repair and G2‐phase progression

E2F7 and E2F8 act as tumor suppressors via transcriptional repression of genes involved in S‐phase entry and progression. Previously, we demonstrated that these atypical E2Fs are degraded by APC/C(C) (dh1) during G1 phase of the cell cycle. However, the mechanism driving the downregulation of atypic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yuan, Ruixue, Liu, Qingwu, Segeren, Hendrika A, Yuniati, Laurensia, Guardavaccaro, Daniele, Lebbink, Robert J, Westendorp, Bart, de Bruin, Alain
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6792010/ https://www.ncbi.nlm.nih.gov/pubmed/31475738 http://dx.doi.org/10.15252/embj.2018101430

Ejemplares similares

SCF(βTrCP)-mediated degradation of SHARP1 in triple-negative breast cancer
por: Enriqué Steinberg, Juliana Haydeé, et al.
Publicado: (2023)

Oncogenic RAS sensitizes cells to drug-induced replication stress via transcriptional silencing of P53
por: Segeren, Hendrika A., et al.
Publicado: (2022)

β-TrCP- and Casein Kinase II-Mediated Degradation of Cyclin F Controls Timely Mitotic Progression
por: Mavrommati, Ioanna, et al.
Publicado: (2018)

Collection of cells for single-cell RNA sequencing using high-resolution fluorescence microscopy
por: Segeren, Hendrika A., et al.
Publicado: (2021)

HIF proteins connect the RB-E2F factors to angiogenesis
por: Bakker, Walbert. J., et al.
Publicado: (2013)

E2F7 Is a Potent Inhibitor of Liver Tumor Growth in Adult Mice
por: Moreno, Eva, et al.
Publicado: (2021)

Synergistic functions of E2F7 and E2F8 are critical to suppress stress-induced skin cancer
por: Thurlings, I, et al.
Publicado: (2017)

E2F7 represses a network of oscillating cell cycle genes to control S-phase progression
por: Westendorp, Bart, et al.
Publicado: (2012)

E2F1 proteolysis via SCF‐cyclin F underlies synthetic lethality between cyclin F loss and Chk1 inhibition
por: Burdova, Kamila, et al.
Publicado: (2019)

Tumor suppressors BTG1 and BTG2: Beyond growth control
por: Yuniati, Laurensia, et al.
Publicado: (2018)

SCF(Cyclin F)-dependent degradation of CDC6 suppresses DNA re-replication
por: Walter, David, et al.
Publicado: (2016)

Atypical E2f functions are critical for pancreas polyploidization
por: Matondo, Ramadhan B., et al.
Publicado: (2018)

The deubiquitylase USP7 is a novel cyclin F-interacting protein and regulates cyclin F protein stability
por: Sharma, Savitha S., et al.
Publicado: (2022)

SCF(Cyclin F) controls centrosome homeostasis and mitotic fidelity via CP110 degradation
por: D’Angiolella, Vincenzo, et al.
Publicado: (2010)

Cyclin F drives proliferation through SCF-dependent degradation of the retinoblastoma-like tumor suppressor p130/RBL2
por: Enrico, Taylor P, et al.
Publicado: (2021)

Chk1 and 14‐3‐3 proteins inhibit atypical E2Fs to prevent a permanent cell cycle arrest
por: Yuan, Ruixue, et al.
Publicado: (2018)

Degradation of cyclin B is critical for nuclear division in Trypanosoma brucei
por: Hayashi, Hanako, et al.
Publicado: (2018)

Cyclin F/FBXO1 Interacts with HIV-1 Viral Infectivity Factor (Vif) and Restricts Progeny Virion Infectivity by Ubiquitination and Proteasomal Degradation of Vif Protein through SCF(cyclin F) E3 Ligase Machinery
por: Augustine, Tracy, et al.
Publicado: (2017)

Potential role of cyclin F mRNA expression in the survival of skin melanoma patients: Comprehensive analysis of the pathways altered due to cyclin F upregulation
por: Gagat, Maciej, et al.
Publicado: (2018)

Casein kinase II phosphorylation of cyclin F at serine 621 regulates the Lys48-ubiquitylation E3 ligase activity of the SCF((cyclin F)) complex
por: Lee, Albert, et al.
Publicado: (2017)

Cyclin F is involved in response to cisplatin treatment in melanoma cell lines
por: Krajewski, Adrian, et al.
Publicado: (2020)

ALS-linked loss of Cyclin-F function affects HSP90
por: Siebert, Alexander, et al.
Publicado: (2022)

Precision measurement of the structure function ratios $F_{2}^{He}/F_{2}^{D}, F_{2}^{C}/F_{2}^{D}$ and $F_{2}^{Ca}/F_{2}^{D}$
por: Amaudruz, P A, et al.
Publicado: (1991)

E2F1 interactions with hHR23A inhibit its degradation and promote DNA repair
por: Singh, Randeep K., et al.
Publicado: (2016)

F-Box Protein FBXO31 Mediates Cyclin D1 Degradation to Induce G1 Arrest Following DNA Damage
por: Santra, Manas K., et al.
Publicado: (2009)

A re-evaluation of $F_{2}^{n}/F_{2}^{p}$ and $F_{2}^{p}-F_{2}^{n}$
por: Arneodo, M, et al.
Publicado: (1993)

The critical role of cyclin D2 in adult neurogenesis
por: Kowalczyk, Anna, et al.
Publicado: (2004)

siRNA Delivery for Control of Cyclin D1 and E2F1 Expression in Crohn’s Disease
por: Russo, Ilaria, et al.
Publicado: (2018)

siRNA Delivery for Control of Cyclin D1 and E2F1 Expression in Crohn’s Disease
por: Russo, Ilaria, et al.
Publicado: (2018)

F-Box Protein Specificity for G1 Cyclins Is Dictated by Subcellular Localization
por: Landry, Benjamin D., et al.
Publicado: (2012)

F box protein FBXL2 exerts human lung tumor suppressor-like activity by ubiquitin-mediated degradation of cyclin D3 resulting in cell cycle arrest
por: Chen, Bill B., et al.
Publicado: (2011)

Results on the ratio $F_{2}^{n}/ F_{2}^{p}$ and on the absolute structure functions $F_{2}^{p}$ , $F_{2}^{d}$
por: Nassalski, J P
Publicado: (1992)

The structure function ratios $F_{2}^{Li}/F_{2}^{D}$ and $F_{2}^{C}/F_{2}^{D}$ at small $x$
por: Arneodo, M., et al.
Publicado: (1995)

Expression of Genomic Instability-Related Molecules: Cyclin F, RRM2 and SPDL1 and Their Prognostic Significance in Pancreatic Adenocarcinoma
por: Klimaszewska-Wiśniewska, Anna, et al.
Publicado: (2021)

CHREBP suppresses gastric cancer progression via the cyclin D1-Rb-E2F1 pathway
por: Zhang, Jianming, et al.
Publicado: (2022)

Saturation of structure function ratios $F_{2}^{Li}/F_{2}^{D}$ and $F_{2}^{C}/F_{2}^{D}$ at small $x$
por: Paic, A
Publicado: (1995)

Exploiting Cross-Luminescence in BaF$_2$ for Ultrafast Timing Applications Using Deep-Ultraviolet Sensitive HPK Silicon Photomultipliers
por: Pots, Rosalinde Hendrika, et al.
Publicado: (2020)

The $F_{2}$ structure function of the proton, of the deuteron and the ratio $F_{2}^{n}/F_{2}^{p}$
por: Oberski, J
Publicado: (1995)

ATR activity controls stem cell quiescence via the cyclin F–SCF complex
por: Salvi, Jayesh S., et al.
Publicado: (2022)

A comparative study of the degradation of yeast cyclins Cln1 and Cln2
por: Quilis, Inma, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_4r5k21abgntovta46c2rbrbgbd