Prdx4 limits caspase‐1 activation and restricts inflammasome‐mediated signaling by extracellular vesicles

Inflammasomes are cytosolic protein complexes, which orchestrate the maturation of active IL‐1β by proteolytic cleavage via caspase‐1. Although many principles of inflammasome activation have been described, mechanisms that limit inflammasome‐dependent immune responses remain poorly defined. Here, w...

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Detalles Bibliográficos
Autores principales: Lipinski, Simone, Pfeuffer, Steffen, Arnold, Philipp, Treitz, Christian, Aden, Konrad, Ebsen, Henriette, Falk‐Paulsen, Maren, Gisch, Nicolas, Fazio, Antonella, Kuiper, Jan, Luzius, Anne, Billmann‐Born, Susanne, Schreiber, Stefan, Nuñez, Gabriel, Beer, Hans‐Dietmar, Strowig, Till, Lamkanfi, Mohamed, Tholey, Andreas, Rosenstiel, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6792017/
https://www.ncbi.nlm.nih.gov/pubmed/31544965
http://dx.doi.org/10.15252/embj.2018101266

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