GladiaTOX: GLobal Assessment of Dose-IndicAtor in TOXicology

SUMMARY: GladiaTOX R package is an open-source, flexible solution to high-content screening data processing and reporting in biomedical research. GladiaTOX takes advantage of the ‘tcpl’ core functionalities and provides a number of extensions: it provides a web-service solution to fetch raw data; it...

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Autores principales: Belcastro, Vincenzo, Cano, Stephane, Marescotti, Diego, Acali, Stefano, Poussin, Carine, Gonzalez-Suarez, Ignacio, Martin, Florian, Bonjour, Filipe, Ivanov, Nikolai V, Peitsch, Manuel C, Hoeng, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6792086/
https://www.ncbi.nlm.nih.gov/pubmed/30873538
http://dx.doi.org/10.1093/bioinformatics/btz187
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author Belcastro, Vincenzo
Cano, Stephane
Marescotti, Diego
Acali, Stefano
Poussin, Carine
Gonzalez-Suarez, Ignacio
Martin, Florian
Bonjour, Filipe
Ivanov, Nikolai V
Peitsch, Manuel C
Hoeng, Julia
author_facet Belcastro, Vincenzo
Cano, Stephane
Marescotti, Diego
Acali, Stefano
Poussin, Carine
Gonzalez-Suarez, Ignacio
Martin, Florian
Bonjour, Filipe
Ivanov, Nikolai V
Peitsch, Manuel C
Hoeng, Julia
author_sort Belcastro, Vincenzo
collection PubMed
description SUMMARY: GladiaTOX R package is an open-source, flexible solution to high-content screening data processing and reporting in biomedical research. GladiaTOX takes advantage of the ‘tcpl’ core functionalities and provides a number of extensions: it provides a web-service solution to fetch raw data; it computes severity scores and exports ToxPi formatted files; furthermore it contains a suite of functionalities to generate PDF reports for quality control and data processing. AVAILABILITY AND IMPLEMENTATION: GladiaTOX R package (bioconductor). Also available via: git clone https://github.com/philipmorrisintl/GladiaTOX.git. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
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spelling pubmed-67920862019-10-18 GladiaTOX: GLobal Assessment of Dose-IndicAtor in TOXicology Belcastro, Vincenzo Cano, Stephane Marescotti, Diego Acali, Stefano Poussin, Carine Gonzalez-Suarez, Ignacio Martin, Florian Bonjour, Filipe Ivanov, Nikolai V Peitsch, Manuel C Hoeng, Julia Bioinformatics Applications Notes SUMMARY: GladiaTOX R package is an open-source, flexible solution to high-content screening data processing and reporting in biomedical research. GladiaTOX takes advantage of the ‘tcpl’ core functionalities and provides a number of extensions: it provides a web-service solution to fetch raw data; it computes severity scores and exports ToxPi formatted files; furthermore it contains a suite of functionalities to generate PDF reports for quality control and data processing. AVAILABILITY AND IMPLEMENTATION: GladiaTOX R package (bioconductor). Also available via: git clone https://github.com/philipmorrisintl/GladiaTOX.git. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online. Oxford University Press 2019-10-15 2019-03-14 /pmc/articles/PMC6792086/ /pubmed/30873538 http://dx.doi.org/10.1093/bioinformatics/btz187 Text en © The Author(s) 2019. Published by Oxford University Press. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Applications Notes
Belcastro, Vincenzo
Cano, Stephane
Marescotti, Diego
Acali, Stefano
Poussin, Carine
Gonzalez-Suarez, Ignacio
Martin, Florian
Bonjour, Filipe
Ivanov, Nikolai V
Peitsch, Manuel C
Hoeng, Julia
GladiaTOX: GLobal Assessment of Dose-IndicAtor in TOXicology
title GladiaTOX: GLobal Assessment of Dose-IndicAtor in TOXicology
title_full GladiaTOX: GLobal Assessment of Dose-IndicAtor in TOXicology
title_fullStr GladiaTOX: GLobal Assessment of Dose-IndicAtor in TOXicology
title_full_unstemmed GladiaTOX: GLobal Assessment of Dose-IndicAtor in TOXicology
title_short GladiaTOX: GLobal Assessment of Dose-IndicAtor in TOXicology
title_sort gladiatox: global assessment of dose-indicator in toxicology
topic Applications Notes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6792086/
https://www.ncbi.nlm.nih.gov/pubmed/30873538
http://dx.doi.org/10.1093/bioinformatics/btz187
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