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SCL: a lattice-based approach to infer 3D chromosome structures from single-cell Hi-C data
MOTIVATION: In contrast to population-based Hi-C data, single-cell Hi-C data are zero-inflated and do not indicate the frequency of proximate DNA segments. There are a limited number of computational tools that can model the 3D structures of chromosomes based on single-cell Hi-C data. RESULTS: We de...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6792089/ https://www.ncbi.nlm.nih.gov/pubmed/30865261 http://dx.doi.org/10.1093/bioinformatics/btz181 |