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Limited Chemical Structural Diversity Found to Modulate Thyroid Hormone Receptor in the Tox21 Chemical Library
BACKGROUND: Thyroid hormone receptors (TRs) are critical endocrine receptors that regulate a multitude of processes in adult and developing organisms, and thyroid hormone disruption is of high concern for neurodevelopmental and reproductive toxicities in particular. To date, only a small number of c...
Autores principales: | Paul-Friedman, Katie, Martin, Matt, Crofton, Kevin M., Hsu, Chia-Wen, Sakamuru, Srilatha, Zhao, Jinghua, Xia, Menghang, Huang, Ruili, Stavreva, Diana A., Soni, Vikas, Varticovski, Lyuba, Raziuddin, Razi, Hager, Gordon L., Houck, Keith A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Environmental Health Perspectives
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6792352/ https://www.ncbi.nlm.nih.gov/pubmed/31566444 http://dx.doi.org/10.1289/EHP5314 |
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