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Advanced Glycation End Products (AGEs) Induce Apoptosis of Fibroblasts by Activation of NLRP3 Inflammasome via Reactive Oxygen Species (ROS) Signaling Pathway

BACKGROUND: Type 2 diabetes impairs the healing process and induces apoptosis of fibroblasts, which are thought to be involved in this process. We investigated the possible mechanisms involved in AGEs-induced apoptosis of human dermal fibroblasts. MATERIAL/METHODS: We examined the expression of apop...

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Detalles Bibliográficos
Autores principales:	Dai, Jiezhi, Chen, Hua, Chai, Yimin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2019
Materias:	Lab/In Vitro Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6792499/ https://www.ncbi.nlm.nih.gov/pubmed/31587010 http://dx.doi.org/10.12659/MSM.915806

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