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Engineered oncolytic virus for the treatment of cholesteatoma: A pilot in vivo study
OBJECTIVE: Determine if oncolytic herpes simplex virus (oHSV) can eradicate cholesteatoma (CHST) in a gerbil model. METHODS: An in vivo model of CHST was developed in Mongolian gerbils by combining Pseudomonas aeruginosa inoculation with double ligation of the external auditory canal (EAC). CHST siz...
Autores principales: | Samy, Ravi N., Earl, Brian R., Lipschitz, Noga, Schweinzger, Ivy, Currier, Mark, Cripe, Timothy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6793611/ https://www.ncbi.nlm.nih.gov/pubmed/31637298 http://dx.doi.org/10.1002/lio2.307 |
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