Cargando…

Resurrection of the ancestral RH5 invasion ligand provides a molecular explanation for the origin of P. falciparum malaria in humans

Many important infectious diseases are the result of zoonoses, in which pathogens that normally infect animals acquire mutations that enable the breaching of species barriers to permit the infection of humans. Our understanding of the molecular events that enable host switching are often limited, an...

Descripción completa

Detalles Bibliográficos
Autores principales: Galaway, Francis, Yu, Ryan, Constantinou, Anastasia, Prugnolle, Franck, Wright, Gavin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6793842/
https://www.ncbi.nlm.nih.gov/pubmed/31613878
http://dx.doi.org/10.1371/journal.pbio.3000490