Cargando…
Molecular mechanism of TRPV2 channel modulation by cannabidiol
Transient receptor potential vanilloid 2 (TRPV2) plays a critical role in neuronal development, cardiac function, immunity, and cancer. Cannabidiol (CBD), the non-psychotropic therapeutically active ingredient of Cannabis sativa, is an activator of TRPV2 and also modulates other transient receptor p...
Autores principales: | Pumroy, Ruth A, Samanta, Amrita, Liu, Yuhang, Hughes, Taylor ET, Zhao, Siyuan, Yudin, Yevgen, Rohacs, Tibor, Han, Seungil, Moiseenkova-Bell, Vera Y |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794088/ https://www.ncbi.nlm.nih.gov/pubmed/31566564 http://dx.doi.org/10.7554/eLife.48792 |
Ejemplares similares
-
Structure-based characterization of novel TRPV5 inhibitors
por: Hughes, Taylor ET, et al.
Publicado: (2019) -
Structural insights on TRPV5 gating by endogenous modulators
por: Hughes, Taylor E. T., et al.
Publicado: (2018) -
Structural insights into the molecular mechanism of mouse TRPA1 activation and inhibition
por: Samanta, Amrita, et al.
Publicado: (2018) -
Cannabidiol interactions with voltage-gated sodium channels
por: Sait, Lily Goodyer, et al.
Publicado: (2020) -
Structural basis of the activation of TRPV5 channels by long-chain acyl-Coenzyme-A
por: Lee, Bo-Hyun, et al.
Publicado: (2023)