Eculizumab in atypical hemolytic uremic syndrome: strategies toward restrictive use

With the introduction of the complement C5-inhibitor eculizumab, a new era was entered for patients with atypical hemolytic uremic syndrome (aHUS). Eculizumab therapy very effectively reversed thrombotic microangiopathy and reduced mortality and morbidity. Initial guidelines suggested lifelong treat...

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Detalles Bibliográficos
Autores principales: Wijnsma, Kioa L., Duineveld, Caroline, Wetzels, Jack F. M., van de Kar, Nicole C. A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794245/
https://www.ncbi.nlm.nih.gov/pubmed/30402748
http://dx.doi.org/10.1007/s00467-018-4091-3

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