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Enforced expression of phosphatidylinositol 4-phosphate 5-kinase homolog alters PtdIns(4,5)P(2) distribution and the localization of small G-proteins

The generation of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P(2)) by phosphatidylinositol 4-phosphate 5-kinases (PIP5Ks) is essential for many functions including control of the cytoskeleton, signal transduction, and endocytosis. Due to its presence in the plasma membrane and anionic charge,...

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Detalles Bibliográficos
Autores principales: Yang, Yanbo, Park, Miriam, Maekawa, Masashi, Fairn, Gregory D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794296/
https://www.ncbi.nlm.nih.gov/pubmed/31616009
http://dx.doi.org/10.1038/s41598-019-51272-z