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Hepcidin and Anemia: A Tight Relationship

Hepcidin, the master regulator of systemic iron homeostasis, tightly influences erythrocyte production. High hepcidin levels block intestinal iron absorption and macrophage iron recycling, causing iron restricted erythropoiesis and anemia. Low hepcidin levels favor bone marrow iron supply for hemogl...

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Detalles Bibliográficos
Autores principales: Pagani, Alessia, Nai, Antonella, Silvestri, Laura, Camaschella, Clara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794341/
https://www.ncbi.nlm.nih.gov/pubmed/31649559
http://dx.doi.org/10.3389/fphys.2019.01294