Cargando…

Local Delivery of Therapeutics to the Inner Ear: The State of the Science

Background: Advances in the understanding of the genetic and molecular etiologies of inner ear disorders have enabled the identification of therapeutic targets and innovative delivery approaches to the inner ear. As this field grows, the need for knowledge about effective delivery of therapeutics to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Anderson, Caroline R., Xie, Carol, Su, Matthew P., Garcia, Maria, Blackshaw, Helen, Schilder, Anne G. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Cellular Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794458/ https://www.ncbi.nlm.nih.gov/pubmed/31649507 http://dx.doi.org/10.3389/fncel.2019.00418

Ejemplares similares

Inner Ear Therapeutics: An Overview of Middle Ear Delivery
por: Patel, Jaimin, et al.
Publicado: (2019)

Nanocarriers for Inner Ear Disease Therapy
por: Xu, Xiaoxiang, et al.
Publicado: (2021)

Organotypic Culture of Neonatal Murine Inner Ear Explants
por: Ogier, Jacqueline M., et al.
Publicado: (2019)

Navigating Hereditary Hearing Loss: Pathology of the Inner Ear
por: Nicolson, Teresa
Publicado: (2021)

Endolymphatic Potential Measured From Developing and Adult Mouse Inner Ear
por: Li, Yi, et al.
Publicado: (2020)

Transcription Factor Reprogramming in the Inner Ear: Turning on Cell Fate Switches to Regenerate Sensory Hair Cells
por: Iyer, Amrita A., et al.
Publicado: (2021)

Inner ear delivery: Challenges and opportunities
por: Szeto, Betsy, et al.
Publicado: (2019)

A Novel Small Molecule Neurotrophin-3 Analogue Promotes Inner Ear Neurite Outgrowth and Synaptogenesis In vitro
por: Kempfle, Judith S., et al.
Publicado: (2021)

Comparison of the Pharmacokinetic Properties of Triamcinolone and Dexamethasone for Local Therapy of the Inner Ear
por: Salt, Alec Nicholas, et al.
Publicado: (2019)

Inner ear therapeutics and the war on hearing loss: systemic barriers to success
por: Jiam, Nicole T., et al.
Publicado: (2023)

Inner Ear Drug Delivery for Sensorineural Hearing Loss: Current Challenges and Opportunities
por: Liu, Sophie S., et al.
Publicado: (2022)

In vivo and in vitro biophysical properties of hair cells from the lateral line and inner ear of developing and adult zebrafish
por: Olt, Jennifer, et al.
Publicado: (2014)

Sphingosine 1-phosphate signaling pathway in inner ear biology. New therapeutic strategies for hearing loss?
por: Romero-Guevara, Ricardo, et al.
Publicado: (2015)

Dopaminergic Inhibition of Na(+) Currents in Vestibular Inner Ear Afferents
por: Meredith, Frances L., et al.
Publicado: (2021)

Characterizing the Access of Cholinergic Antagonists to Efferent Synapses in the Inner Ear
por: Lee, Choongheon, et al.
Publicado: (2021)

Meta-Analysis of Down Syndrome Cortical Development Reveals Underdeveloped State of the Science
por: Risgaard, Kirstin A., et al.
Publicado: (2022)

Local Cisplatin Delivery in Mouse Reliably Models Sensorineural Ototoxicity Without Systemic Adverse Effects
por: Nacher-Soler, German, et al.
Publicado: (2021)

Nanoparticle mediated drug delivery of rolipram to tyrosine kinase B positive cells in the inner ear with targeting peptides and agonistic antibodies
por: Glueckert, Rudolf, et al.
Publicado: (2015)

The Repression of Atoh1 by Neurogenin1 during Inner Ear Development
por: Gálvez, Héctor, et al.
Publicado: (2017)

Rapid mechanical stimulation of inner-ear hair cells by photonic pressure
por: Abeytunge, Sanjeewa, et al.
Publicado: (2021)

Erratum: Dopaminergic Inhibition of Na(+) Currents in Vestibular Inner Ear Afferents
por: Frontiers Production Office,
Publicado: (2022)

Calretinin Immunoreactivity in the VIIIth Nerve and Inner Ear Endorgans of Ranid Frogs
por: Reichenberger, Ingrid, et al.
Publicado: (2021)

Unlocking the human inner ear for therapeutic intervention
por: Li, Hao, et al.
Publicado: (2022)

Ca(2+) Regulates the Kinetics of Synaptic Vesicle Fusion at the Afferent Inner Hair Cell Synapse
por: Huang, Chao-Hua, et al.
Publicado: (2018)

Inner Ear Diagnostics and Drug Delivery via Microneedles
por: Leong, Stephen, et al.
Publicado: (2022)

Inner Ear
por: Arnold, Andreas, et al.
Publicado: (2010)

Patch Clamp Recordings in Inner Ear Hair Cells Isolated from Zebrafish
por: Einarsson, Rachel, et al.
Publicado: (2012)

Epigenetic regulation in the inner ear and its potential roles in development, protection, and regeneration
por: Layman, Wanda S., et al.
Publicado: (2015)

Inner ear hair cells deteriorate in mice engineered to have no or diminished innervation
por: Kersigo, Jennifer, et al.
Publicado: (2015)

Expression and Physiology of Voltage-Gated Sodium Channels in Developing Human Inner Ear
por: Quinn, Rikki K., et al.
Publicado: (2021)

Editorial: The mechanism on development and regeneration of inner ear hair cells
por: Sun, Haojie, et al.
Publicado: (2022)

Bovine serum albumin nanoparticles as controlled release carrier for local drug delivery to the inner ear
por: Yu, Zhan, et al.
Publicado: (2014)

In vivo Morphometry of Inner Plexiform Layer (IPL) Stratification in the Human Retina With Visible Light Optical Coherence Tomography
por: Zhang, Tingwei, et al.
Publicado: (2021)

Understanding the translocation mechanism of PLGA nanoparticles across round window membrane into the inner ear: a guideline for inner ear drug delivery based on nanomedicine
por: Zhang, Liping, et al.
Publicado: (2018)

Gross and Fine Dissection of Inner Ear Sensory Epithelia in Adult Zebrafish (Danio rerio)
por: Liang, Jin, et al.
Publicado: (2009)

Hearing Loss Controlled by Optogenetic Stimulation of Nonexcitable Nonglial Cells in the Cochlea of the Inner Ear
por: Sato, Mitsuo P., et al.
Publicado: (2017)

Fzd3 Expression Within Inner Ear Afferent Neurons Is Necessary for Central Pathfinding
por: Stoner, Zachary A., et al.
Publicado: (2022)

Deep intracochlear injection of triamcinolone-acetonide with an inner ear catheter in patients with residual hearing
por: Prenzler, Nils K., et al.
Publicado: (2023)

Inner ear barriers to nanomedicine-augmented drug delivery and imaging()
por: Zou, Jing, et al.
Publicado: (2016)

Gentamicin delivery to the inner ear: Does endolymphatic hydrops matter?
por: Marques, Pedro, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_a972k13180n69j59o4p85fhfn8