Modulation of TLR4 Sialylation Mediated by a Sialidase Neu1 and Impairment of Its Signaling in Leishmania donovani Infected Macrophages

Altered sialylation is generally maintained by a fine balance between sialidases and sialyltransferases, which plays an essential role during disease pathogenesis. TLR4 is a membrane-bound highly sialylated glycoprotein predominantly having α2,3-linked sialic acids. It is one of the most important c...

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Detalles Bibliográficos
Autores principales: Karmakar, Joyshree, Roy, Saptarshi, Mandal, Chitra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794462/
https://www.ncbi.nlm.nih.gov/pubmed/31649671
http://dx.doi.org/10.3389/fimmu.2019.02360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794462/
https://www.ncbi.nlm.nih.gov/pubmed/31649671
http://dx.doi.org/10.3389/fimmu.2019.02360

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