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Evolutionary Trends in RNA Base Selectivity Within the RNase A Superfamily
There is a growing interest in the pharmaceutical industry to design novel tailored drugs for RNA targeting. The vertebrate-specific RNase A superfamily is nowadays one of the best characterized family of enzymes and comprises proteins involved in host defense with specific cytotoxic and immune-modu...
Autores principales: | Prats-Ejarque, Guillem, Lu, Lu, Salazar, Vivian A., Moussaoui, Mohammed, Boix, Ester |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794472/ https://www.ncbi.nlm.nih.gov/pubmed/31649540 http://dx.doi.org/10.3389/fphar.2019.01170 |
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