Atorvastatin Exerts Antileukemia Activity via Inhibiting Mevalonate-YAP Axis in K562 and HL60 Cells

Novel therapeutic strategies are still urgently expected for leukemia despite undisputed success of various targeted therapeutics. The antileukemia activity of Atorvastatin, a 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, on human leukemia cells was investigated. Atorvastatin...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Chen, Ting, Dou, Yonghai, Zhang, Shaolu, Liu, Hongyan, Khishignyam, Tungalagtamir, Li, Xiaofei, Zuo, Duo, Zhang, Zhe, Jin, Meihua, Wang, Ran, Qiu, Yuling, Zhong, YuXu, Kong, Dexin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794561/
https://www.ncbi.nlm.nih.gov/pubmed/31649888
http://dx.doi.org/10.3389/fonc.2019.01032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794561/
https://www.ncbi.nlm.nih.gov/pubmed/31649888
http://dx.doi.org/10.3389/fonc.2019.01032

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