The CRISPR‐Cas13a Gene‐Editing System Induces Collateral Cleavage of RNA in Glioma Cells

RNA is rarely used as a therapeutic target due to its flexible structure and instability. CRISPR‐Cas13a is a powerful tool for RNA knockdown, and the potential application of CRISPR‐Cas13a in cancer cells should be further studied. In this study, overexpression of LwCas13a by lentivirus in glioma ce...

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Detalles Bibliográficos
Autores principales: Wang, Qixue, Liu, Xing, Zhou, Junhu, Yang, Chao, Wang, Guangxiu, Tan, Yanli, Wu, Ye, Zhang, Sijing, Yi, Kaikai, Kang, Chunsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794629/
https://www.ncbi.nlm.nih.gov/pubmed/31637166
http://dx.doi.org/10.1002/advs.201901299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794629/
https://www.ncbi.nlm.nih.gov/pubmed/31637166
http://dx.doi.org/10.1002/advs.201901299

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