Intraportally delivered stem cell spheroids localize in the liver and protect hepatocytes against GalN/LPS-induced fulminant hepatic toxicity

BACKGROUND: Systemic inflammatory response syndrome (SIRS) is common in severe fulminant hepatic failure (FHF) and has a high mortality rate (20–50%) due to irreversible cerebral edema or sepsis. Stem cell-based treatment has emerged as a promising alternative therapeutic strategy to prolong the sur...

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Detalles Bibliográficos
Autores principales: Regmi, Shobha, Pathak, Shiva, Thanh, Tung Pham, Nguyen, Tiep Tien, Sung, Jong-Hyuk, Yook, Simmyung, Kim, Jong Oh., Yong, Chul Soon, Choi, Inho, Doh, Kyoung-Oh, Park, Pil-Hoon, Park, Jun-Beom, Seo, Yoojin, Kim, Bieong-Kil, Lee, Dong-Mok, Moon, Ik-Jae, Kim, Hyung-Sik, Jeong, Jee-Heon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794806/
https://www.ncbi.nlm.nih.gov/pubmed/31615539
http://dx.doi.org/10.1186/s13287-019-1337-3

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