Long noncoding RNA GAS5 inhibits progression of colorectal cancer by interacting with and triggering YAP phosphorylation and degradation and is negatively regulated by the m(6)A reader YTHDF3

BACKGROUND: YAP activation is crucial for cancer development including colorectal cancer (CRC). Nevertheless, it remains unclear whether N6-Methyladenosine (m(6)A) modified transcripts of long noncoding RNAs (lncRNAs) can regulate YAP activation in cancer progression. We investigated the functional...

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Detalles Bibliográficos
Autores principales: Ni, Wen, Yao, Su, Zhou, Yunxia, Liu, Yuanyuan, Huang, Piao, Zhou, Aijun, Liu, Jingwen, Che, Liheng, Li, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794841/
https://www.ncbi.nlm.nih.gov/pubmed/31619268
http://dx.doi.org/10.1186/s12943-019-1079-y

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