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Low Frequency of MKRN3 and DLK1 Variants in Chinese Children with Central Precocious Puberty
BACKGROUND: Central precocious puberty (CPP) is defined by gonadotropin-dependent development of secondary sexual characteristics before the age of 8 years in girls and 9 years in boys. MKRN3 and DLK1 are two genes, disease-causing variants of which have recently been discovered to cause idiopathic...
Autores principales: | Chen, Ting, Chen, Linqi, Wu, Haiying, Xie, Rongrong, Wang, Fengyun, Chen, Xiuli, Sun, Hui, Xiao, Fei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794979/ https://www.ncbi.nlm.nih.gov/pubmed/31687022 http://dx.doi.org/10.1155/2019/9879367 |
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