Iron-induced transferrin receptor-1 mRNA destabilization: A response to “Neither miR-7-5p nor miR-141-3p is a major mediator of iron-responsive transferrin receptor-1 mRNA degradation”

We read with great interest the Divergent Views article by Connell and colleagues disputing our recent publication describing a role for two microRNAs in the iron-mediated regulation of transferrin receptor 1 (TfR1) mRNA stability. Our publication sought to shed light on a long-standing question in...

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Detalles Bibliográficos
Autores principales: Miyazawa, Masaki, Bogdan, Alexander R., Hashimoto, Kazunori, Tsuji, Yoshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Divergent Views
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795137/
https://www.ncbi.nlm.nih.gov/pubmed/31511321
http://dx.doi.org/10.1261/rna.073270.119
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author Miyazawa, Masaki
Bogdan, Alexander R.
Hashimoto, Kazunori
Tsuji, Yoshiaki
author_facet Miyazawa, Masaki
Bogdan, Alexander R.
Hashimoto, Kazunori
Tsuji, Yoshiaki
author_sort Miyazawa, Masaki
collection PubMed
description We read with great interest the Divergent Views article by Connell and colleagues disputing our recent publication describing a role for two microRNAs in the iron-mediated regulation of transferrin receptor 1 (TfR1) mRNA stability. Our publication sought to shed light on a long-standing question in the field of cellular iron metabolism, and we welcome commentary and critique. However, there are several critical issues contained in the article by Connell and colleagues that require further consideration. We appreciate the opportunity to reply here.
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spelling pubmed-67951372020-11-01 Iron-induced transferrin receptor-1 mRNA destabilization: A response to “Neither miR-7-5p nor miR-141-3p is a major mediator of iron-responsive transferrin receptor-1 mRNA degradation” Miyazawa, Masaki Bogdan, Alexander R. Hashimoto, Kazunori Tsuji, Yoshiaki RNA Divergent Views We read with great interest the Divergent Views article by Connell and colleagues disputing our recent publication describing a role for two microRNAs in the iron-mediated regulation of transferrin receptor 1 (TfR1) mRNA stability. Our publication sought to shed light on a long-standing question in the field of cellular iron metabolism, and we welcome commentary and critique. However, there are several critical issues contained in the article by Connell and colleagues that require further consideration. We appreciate the opportunity to reply here. Cold Spring Harbor Laboratory Press 2019-11 /pmc/articles/PMC6795137/ /pubmed/31511321 http://dx.doi.org/10.1261/rna.073270.119 Text en © 2019 Miyazawa et al.; Published by Cold Spring Harbor Laboratory Press for the RNA Society http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed exclusively by the RNA Society for the first 12 months after the full-issue publication date (see http://rnajournal.cshlp.org/site/misc/terms.xhtml). After 12 months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Divergent Views
Miyazawa, Masaki
Bogdan, Alexander R.
Hashimoto, Kazunori
Tsuji, Yoshiaki
Iron-induced transferrin receptor-1 mRNA destabilization: A response to “Neither miR-7-5p nor miR-141-3p is a major mediator of iron-responsive transferrin receptor-1 mRNA degradation”
title Iron-induced transferrin receptor-1 mRNA destabilization: A response to “Neither miR-7-5p nor miR-141-3p is a major mediator of iron-responsive transferrin receptor-1 mRNA degradation”
title_full Iron-induced transferrin receptor-1 mRNA destabilization: A response to “Neither miR-7-5p nor miR-141-3p is a major mediator of iron-responsive transferrin receptor-1 mRNA degradation”
title_fullStr Iron-induced transferrin receptor-1 mRNA destabilization: A response to “Neither miR-7-5p nor miR-141-3p is a major mediator of iron-responsive transferrin receptor-1 mRNA degradation”
title_full_unstemmed Iron-induced transferrin receptor-1 mRNA destabilization: A response to “Neither miR-7-5p nor miR-141-3p is a major mediator of iron-responsive transferrin receptor-1 mRNA degradation”
title_short Iron-induced transferrin receptor-1 mRNA destabilization: A response to “Neither miR-7-5p nor miR-141-3p is a major mediator of iron-responsive transferrin receptor-1 mRNA degradation”
title_sort iron-induced transferrin receptor-1 mrna destabilization: a response to “neither mir-7-5p nor mir-141-3p is a major mediator of iron-responsive transferrin receptor-1 mrna degradation”
topic Divergent Views
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795137/
https://www.ncbi.nlm.nih.gov/pubmed/31511321
http://dx.doi.org/10.1261/rna.073270.119
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