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Predictability of individual circadian phase during daily routine for medical applications of circadian clocks
BACKGROUND: Circadian timing of treatments can largely improve tolerability and efficacy in patients. Thus, drug metabolism and cell cycle are controlled by molecular clocks in each cell and coordinated by the core body temperature 24-hour rhythm, which is generated by the hypothalamic pacemaker. In...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Clinical Investigation
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795290/ https://www.ncbi.nlm.nih.gov/pubmed/31430260 http://dx.doi.org/10.1172/jci.insight.130423 |