Review on the One-year Repeated Dose Oral Toxicity Study in Dogs for the Toxicological Evaluation of Pesticides (Agricultural Chemicals) (Decision of the Expert Committee on Pesticide, FSCJ, 21 December 2017)

In the toxicological evaluation of pesticides (agricultural chemicals), their toxicities have been evaluated based on studies in rodents such as rats and mice as well as in non-rodents such as rabbits and dogs. Here, reflecting a research performed under the Food Safety Commission of Japan (FSCJ) gr...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Food Safety Commission, Cabinet Office, Government of Japan 2018
Materias:
Risk Assessment Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795391/
https://www.ncbi.nlm.nih.gov/pubmed/31998579
http://dx.doi.org/10.14252/foodsafetyfscj.2018008s
Descripción
Sumario:In the toxicological evaluation of pesticides (agricultural chemicals), their toxicities have been evaluated based on studies in rodents such as rats and mice as well as in non-rodents such as rabbits and dogs. Here, reflecting a research performed under the Food Safety Commission of Japan (FSCJ) grant on pesticide toxicity study(1)), international trends and also scientific points of view, the necessity of chronic dog toxicity studies was reconsidered for the use in toxicological evaluation of pesticides.

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