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The effects of manipulating levels of replication initiation factors on origin firing efficiency in yeast

Chromosome replication in Saccharomyces cerevisiae is initiated from ~300 origins that are regulated by DNA sequence and by the limited abundance of six trans-acting initiation proteins (Sld2, Sld3, Dpb11, Dbf4, Sld7 and Cdc45). We set out to determine how the levels of individual factors contribute...

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Detalles Bibliográficos
Autores principales:	Lynch, Kelsey L., Alvino, Gina M., Kwan, Elizabeth X., Brewer, Bonita J., Raghuraman, M. K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795477/ https://www.ncbi.nlm.nih.gov/pubmed/31584938 http://dx.doi.org/10.1371/journal.pgen.1008430

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