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Metabolic Disturbances of a High-Fat Diet Are Dependent on APOE Genotype and Sex
Apolipoprotein E4 (APOE4) is the strongest genetic risk factor for Alzheimer’s disease (AD). APOE4 is also associated with an increased risk of metabolic syndrome. Obesity is a major environmental risk factor for AD. While APOE genotype and obesity independently affect metabolism and cognition, they...
Autores principales: | Jones, Nahdia S., Watson, Katarina Q., Rebeck, G. William |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795556/ https://www.ncbi.nlm.nih.gov/pubmed/31554665 http://dx.doi.org/10.1523/ENEURO.0267-19.2019 |
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