Cargando…

Mitophagy in Hepatic Insulin Resistance: Therapeutic Potential and Concerns

Metabolic syndrome, characterized by central obesity, hypertension, and hyperlipidemia, increases the morbidity and mortality of cardiovascular disease, type 2 diabetes, nonalcoholic fatty liver disease, and other metabolic diseases. It is well known that insulin resistance, especially hepatic insul...

Descripción completa

Detalles Bibliográficos
Autores principales:	Su, Zuqing, Nie, Yutong, Huang, Xiufang, Zhu, Ying, Feng, Bing, Tang, Lipeng, Zheng, Guangjuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795753/ https://www.ncbi.nlm.nih.gov/pubmed/31649547 http://dx.doi.org/10.3389/fphar.2019.01193

Ejemplares similares

Phytochemicals: Targeting Mitophagy to Treat Metabolic Disorders
por: Su, Zuqing, et al.
Publicado: (2021)

Kun-Dan Decoction Ameliorates Insulin Resistance by Activating AMPK/mTOR-Mediated Autophagy in High-Fat Diet-Fed Rats
por: Su, Zuqing, et al.
Publicado: (2021)

Punicalagin Alleviates Psoriasis by Inhibiting NF-κB-Mediated IL-1β Transcription and Caspase-1-Regulated IL-1β Secretion
por: Tang, Lipeng, et al.
Publicado: (2022)

Mitophagy: A potential therapeutic target for insulin resistance
por: Ning, Peng, et al.
Publicado: (2022)

Optineurin-mediated mitophagy as a potential therapeutic target for intervertebral disc degeneration
por: Hu, Zhilei, et al.
Publicado: (2022)

Pyroptosis: A promising therapeutic target for noninfectious diseases
por: Li, Tong, et al.
Publicado: (2021)

Hydroxychloroquine Improves Obesity-Associated Insulin Resistance and Hepatic Steatosis by Regulating Lipid Metabolism
por: Qiao, Xin, et al.
Publicado: (2019)

Therapeutic Mechanisms of Herbal Medicines Against Insulin Resistance: A Review
por: Li, Jun, et al.
Publicado: (2019)

Administration of protopine prevents mitophagy and acute lung injury in sepsis
por: Xiao, Zhong, et al.
Publicado: (2023)

Mesaconine alleviates doxorubicin-triggered cardiotoxicity and heart failure by activating PINK1-dependent cardiac mitophagy
por: Zhou, Ji-Chao, et al.
Publicado: (2023)

Potential Nexus of Non-alcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus: Insulin Resistance Between Hepatic and Peripheral Tissues
por: Mu, Wan, et al.
Publicado: (2019)

Gerontoxanthone I and Macluraxanthone Induce Mitophagy and Attenuate Ischemia/Reperfusion Injury
por: Xiang, Qian, et al.
Publicado: (2020)

Immune and Metabolic Regulation Mechanism of Dangguiliuhuang Decoction against Insulin Resistance and Hepatic Steatosis
por: Cao, Hui, et al.
Publicado: (2017)

Mitophagy-mediated adipose inflammation contributes to type 2 diabetes with hepatic insulin resistance
por: He, Feng, et al.
Publicado: (2020)

Berberine suppressed sarcopenia insulin resistance through SIRT1-mediated mitophagy
por: Su, Xiaojuan, et al.
Publicado: (2023)

Identification of super-enhancer-driven peptidyl arginine deiminases as potential biomarkers and therapeutic targets for osimertinib-resistant non-small cell lung cancer
por: Li, Hang, et al.
Publicado: (2022)

Triggering of Parkin Mitochondrial Translocation in Mitophagy: Implications for Liver Diseases
por: Eid, Nabil, et al.
Publicado: (2016)

Kininase 1 As a Preclinical Therapeutic Target for Kinin B(1) Receptor in Insulin Resistance
por: Haddad, Youssef, et al.
Publicado: (2017)

Editorial: Hepatic insulin resistance and related obesity: highlighting the ameliorative role of nutraceuticals, dietary intervention, and pharmaceuticals
por: Ramadan, Nehal M., et al.
Publicado: (2023)

Role of NLRP3 inflammasome and oxidative stress in hepatic insulin resistance and the ameliorative effect of phytochemical intervention
por: de Deus, Isabela Jesus, et al.
Publicado: (2023)

Vitamin K2 Can Rescue the Dexamethasone-Induced Downregulation of Osteoblast Autophagy and Mitophagy Thereby Restoring Osteoblast Function In Vitro and In Vivo
por: Chen, Liang, et al.
Publicado: (2020)

Emerging Role of Mitophagy in the Heart: Therapeutic Potentials to Modulate Mitophagy in Cardiac Diseases
por: Luan, Yi, et al.
Publicado: (2021)

Advances in mitophagy and mitochondrial apoptosis pathway-related drugs in glioblastoma treatment
por: Li, Weiping, et al.
Publicado: (2023)

Src Activation Aggravates Podocyte Injury in Diabetic Nephropathy via Suppression of FUNDC1-Mediated Mitophagy
por: Zheng, Ting, et al.
Publicado: (2022)

Erythropoietin Mitigates Diabetic Nephropathy by Restoring PINK1/Parkin-Mediated Mitophagy
por: Yi, Xinyao, et al.
Publicado: (2022)

Emerging insights on the role of gasdermins in infection and inflammatory diseases
por: Tang, Lipeng, et al.
Publicado: (2020)

miR-378b Regulates Insulin Sensitivity by Targeting Insulin Receptor and p110α in Alcohol-Induced Hepatic Steatosis
por: Li, Yuan-yuan, et al.
Publicado: (2020)

Possible Role of Hydrogen Sulfide in Insulin Secretion and in Development of Insulin Resistance
por: Patel, MA, et al.
Publicado: (2010)

Mitophagy in carcinogenesis, drug resistance and anticancer therapeutics
por: Guan, Yanjie, et al.
Publicado: (2021)

Role of anthraquinones in combating insulin resistance
por: Xia, Wanru, et al.
Publicado: (2023)

Ethanol-Induced Hepatic Insulin Resistance is Ameliorated by Methyl Ferulic Acid Through the PI3K/AKT Signaling Pathway
por: Cheng, Qi, et al.
Publicado: (2019)

Aldehyde Dehydrogenase 2 Protects Against Lipopolysaccharide-Induced Myocardial Injury by Suppressing Mitophagy
por: Ji, Wenqing, et al.
Publicado: (2021)

Type 2 Diabetes Complicated With Heart Failure: Research on Therapeutic Mechanism and Potential Drug Development Based on Insulin Signaling Pathway
por: Ye, Hui, et al.
Publicado: (2022)

Therapeutic Potential of Polyphenols in Cardiac Fibrosis
por: Zhang, Ning, et al.
Publicado: (2018)

Long non‐coding RNAs in cutaneous biology and proliferative skin diseases: Advances and perspectives
por: Tang, Lipeng, et al.
Publicado: (2019)

Vitamin D Attenuates Ischemia/Reperfusion-Induced Cardiac Injury by Reducing Mitochondrial Fission and Mitophagy
por: Lee, Tzu-Lin, et al.
Publicado: (2020)

PPARγ Transcription Deficiency Exacerbates High-Fat Diet-Induced Adipocyte Hypertrophy and Insulin Resistance in Mice
por: Guo, Fusheng, et al.
Publicado: (2020)

Molecular and Clinical Aspects of COVID-19 Vaccines and Other Therapeutic Interventions Apropos Emerging Variants of Concern
por: Islam, Khursheed Ul, et al.
Publicado: (2021)

Therapeutics for fulminant hepatitis caused by enteroviruses in neonates
por: Wang, Li-Chiu, et al.
Publicado: (2022)

Aldehyde Dehydrogenase 2 Has Cardioprotective Effects on Myocardial Ischaemia/Reperfusion Injury via Suppressing Mitophagy
por: Ji, Wenqing, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_k2l704vi7pf0ocqqe88706mu2d