Preclinical evaluation of local prolonged release of paclitaxel from gelatin microspheres for the prevention of recurrence of peritoneal carcinomatosis in advanced ovarian cancer

Patients with advanced ovarian cancer develop recurrence despite initial treatment response to standard treatment of surgery and intravenous/intraperitoneal (IP) chemotherapy, partly due to a limited peritoneal exposure time of chemotherapeutics. Paclitaxel-loaded genipin-crosslinked gelatin microsp...

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Detalles Bibliográficos
Autores principales: De Clercq, Kaat, Xie, Feifan, De Wever, Olivier, Descamps, Benedicte, Hoorens, Anne, Vermeulen, An, Ceelen, Wim, Vervaet, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795903/
https://www.ncbi.nlm.nih.gov/pubmed/31619730
http://dx.doi.org/10.1038/s41598-019-51419-y

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