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Medical Treatment and Dose Estimation of a Person Exposed to Tritium

In this study, we aimed to investigate the damaging effects and clinical therapy of internal contamination with tritium to provide information and gain experience for medical treatments in case of an emergency due to a nuclear accident. Histories were taken by several doctors who observed and record...

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Autores principales: Chen, Weibo, Li, Houwen, Wang, Kongzhao, Bian, Huahui, Wang, Youyou, Cui, Fengmei, Liu, Yulong, Chen, Qiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796214/
https://www.ncbi.nlm.nih.gov/pubmed/31662710
http://dx.doi.org/10.1177/1559325819880670
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author Chen, Weibo
Li, Houwen
Wang, Kongzhao
Bian, Huahui
Wang, Youyou
Cui, Fengmei
Liu, Yulong
Chen, Qiu
author_facet Chen, Weibo
Li, Houwen
Wang, Kongzhao
Bian, Huahui
Wang, Youyou
Cui, Fengmei
Liu, Yulong
Chen, Qiu
author_sort Chen, Weibo
collection PubMed
description In this study, we aimed to investigate the damaging effects and clinical therapy of internal contamination with tritium to provide information and gain experience for medical treatments in case of an emergency due to a nuclear accident. Histories were taken by several doctors who observed and recorded the clinical symptoms of the patient described herein. The general health situation was evaluated by laboratory and equipment analyses. Tritium concentrations in the urine were estimated according to relevant standards during the monitoring period using a liquid scintillation counting method. Clinical observation revealed that the patient had symptoms of mild asthenia and sleep disorder with improvement after appropriate treatment. The last committed effective dose was determined through measurement of the urine tritium concentration and dose estimation and was estimated to be 0.123 mSv; the total effective dose was 14.536 mSv. The medical treatment and dose estimation in this patient with tritium contamination were successful and can provide a reference for similar cases in the future.
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spelling pubmed-67962142019-10-29 Medical Treatment and Dose Estimation of a Person Exposed to Tritium Chen, Weibo Li, Houwen Wang, Kongzhao Bian, Huahui Wang, Youyou Cui, Fengmei Liu, Yulong Chen, Qiu Dose Response Original Article In this study, we aimed to investigate the damaging effects and clinical therapy of internal contamination with tritium to provide information and gain experience for medical treatments in case of an emergency due to a nuclear accident. Histories were taken by several doctors who observed and recorded the clinical symptoms of the patient described herein. The general health situation was evaluated by laboratory and equipment analyses. Tritium concentrations in the urine were estimated according to relevant standards during the monitoring period using a liquid scintillation counting method. Clinical observation revealed that the patient had symptoms of mild asthenia and sleep disorder with improvement after appropriate treatment. The last committed effective dose was determined through measurement of the urine tritium concentration and dose estimation and was estimated to be 0.123 mSv; the total effective dose was 14.536 mSv. The medical treatment and dose estimation in this patient with tritium contamination were successful and can provide a reference for similar cases in the future. SAGE Publications 2019-10-15 /pmc/articles/PMC6796214/ /pubmed/31662710 http://dx.doi.org/10.1177/1559325819880670 Text en © The Author(s) 2019 http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Article
Chen, Weibo
Li, Houwen
Wang, Kongzhao
Bian, Huahui
Wang, Youyou
Cui, Fengmei
Liu, Yulong
Chen, Qiu
Medical Treatment and Dose Estimation of a Person Exposed to Tritium
title Medical Treatment and Dose Estimation of a Person Exposed to Tritium
title_full Medical Treatment and Dose Estimation of a Person Exposed to Tritium
title_fullStr Medical Treatment and Dose Estimation of a Person Exposed to Tritium
title_full_unstemmed Medical Treatment and Dose Estimation of a Person Exposed to Tritium
title_short Medical Treatment and Dose Estimation of a Person Exposed to Tritium
title_sort medical treatment and dose estimation of a person exposed to tritium
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796214/
https://www.ncbi.nlm.nih.gov/pubmed/31662710
http://dx.doi.org/10.1177/1559325819880670
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