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Discovery of New Inhibitors of Hepatitis C Virus NS3/4A Protease and Its D168A Mutant
[Image: see text] Hepatitis C virus (HCV) is a human pathogen with high morbidity. The HCV NS3/4A protease is essential for viral replication and is one of the top three drug targets. Several drugs targeting the protease have been developed, but drug-resistant mutant strains emerged. Here, we screen...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796237/ https://www.ncbi.nlm.nih.gov/pubmed/31646247 http://dx.doi.org/10.1021/acsomega.9b02491 |